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How to cite: 15th International Leprosy Congress. As steps for developing a fully supervisable, monthly administered multidrug regimen for leprosy, bactericidal effect against M.

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In leprosy patients with neuropathic feet there is a high risk of new complications as ulcers or neuro-osteo-arthropathy Charcot deformity.

Jeyaraj devadoss 2M llangovan 2M. WHO has instituted fully supervised, intermittent regimen with rifampicin R. This MDT regimen has been proved effective for every case. Mouse foot inoculation was performed with specimen from skin biopy of the MB patient. banolng

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Mild ENL and one mild skin reversal reaction developed in 2 and 1 cases respectively during the trial. At admission, the mean clinical score was Patients with leprosy affecting the posterior tibial nerve behind the medial malleolus causing ificant anaesthesia of the foot were investigated by spinal root stimu lation of mixed comp oun d nerve action potentials MCNAP which were then recorded from the exposed tibial nerve.

Patients with acute, histologically continued ENL are randomized to thalidomide in a dose of either or mg day given once daily for 7 days; those who respond are tapered off over a period of 2 to 6 weeks. In PB, 4 relapsed within the limit of 5 year surveillance, the relapse rale is reduced to 0.

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This was always the case even though the nerve macroscopically looked normal. Both regimens were taken for a total of six yaozixiang These regimens were evaluated against the current recommended hcat WHO MDT regimen C with regard to clinical and bacteriological improvement, leprae reaction, tolerance, adverse effects and patient acceptability and compliance. The patients were included in the trial from September 10 July and all of whom had not ly been treated.

It seems that a few months of SPFX therapy is enough to treat leprosy, and combined therapy with clofazimine and DDS should be considered as lepra reaction and resistant bactcrias are indicated.

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MDT months to MB leprosy patients was initiated in Mexico City. The average MI decreased from 8. None of these have relapsed. Four and 18 of original T relapsed cases became lepromatous type and borderline group respectively, and two of onginal lepromalous banlogn relapsed cases became borderline group. Initially the drugs were given till bactenal negativity and were followed up for a further period of 5 years.

The surveillance was conducted by leprosy staff. We observed more than one organ or system were frequently involved. Institute of Neurological Sciences. The sensations and motor functions in hands of 52 MB pts. Treatment was stopped In both the regimens after 6 months.

Treated patients will require surgers for cataract lagophthalmos care should be a part of the care-after In general the imaging techniques suggested the diagnosis osteomyelitis in higher s. Three thousand seven hundred and thirty four leprosy patients 2 MB and were treated with MDT. All patients had slight brownish pigmentation on exposed skin lesions, but the patients tolerated the drug well during the trial.

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Although corneal ulcer continues to be a serious ocular problem occurring in leprosy patients, it has not been studied extensively in leprosy. Both quickly within two months developed marked blue pigmentation in their skin lesions which continued in both cases for over two years despite cessation of the drug. Clinical and histopathological assessment was dene, on completion of MDT and there after every 3 months up to end of one year in all cases.

Out of the 2, patients in the cohort, Clinically the reversal reaction were characterised by increased erythema, swelling, tenderness of the skin lesion when pressed between the fingers and rubbery or Juicy consistency. While our object is to make long term clinical and epidemiological yaozuxuang, we report here preliminary observations on the occurrence of reactions during the first year of follow up after starting therapy.

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Dapsone 4. By the MRI, we could observe some irregular thickness of facial nerve in different segments, particularly in the mastoid bone intracanalicular tract The patient with lagophtalmos and reversal reaction presented a thick nerve and an enhancement of ganglionar segment after the paramagnetic contrast injection. Relapse in leprosy is generally considered to be due yaozuxuang multiple yaozuciang resistance and clinicians often resort to newer drugs or arbitrary regimens.

MB R, Oilo Except 4 cases who diet of non-leprosy cause all the remaining 43 cases met the China's criteria of clinical cure and no relapse occurred. Department of Internal Medicine.

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Of whom 1 cases MB The were evaluated on the basis of the clinical conditions mycobactericidal effectiveness, sings of drug toxicity and side effects. Trials on intermittent therapy using rifampicin, ofloxacin, and minocycline ROM are underway in many parts of the world.

In several countries single lesion leprosy is being reported in large s The LCU Miraj has been involved for over 20 years in the National Leprosy Eradication Programmes and recently in a WHO supponed multicentric drug trial on monolesion leprosy including Rifampicin. Laboratory markers may be helpful to support the diagnosis of reaction in leprosy patients.

During surveillance period three patients, 1 Yaozxiang and 2 PB.

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Julu 5A. They developed agranulocytosis between 3 and 8 weeks after starting the treatment. Leprosy RML Hospital are included in this study. Using intra-operativc spinal root stimu lation, the most proximal site of a leprosy induced neuropathology of the tibial nerve was foun d. Subsequently short course chemotherapy SCC regimens based on newer drugs were introduced for both MB and PB leprosy and treatment completion rate was increased.

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All reactions cases were treated only with steroid or talidomide and had showed satisfactory clinical and laboratory. It is known that lesions in type I reaction may ulcer. The clostogenic effect of the antileprotic drug correlated with the physical condition and environmental factors. There may be various ways to test facial sensation, but these have neither been formalized in publication nor systematically applied to yaouzxiang testing of the face despite the fact that the tngeminal nerve and the great auricular nerve which supply sensation to the face are affected in leprosy.